February 2008

Editor's Notebook

The e-ffective Pharmacist
Editor-in-Chief Harold E. Cohen, RPh, believes that electronic prescribing will reduce errors caused by sloppy handwriting, but he still worries about prescriptions that are written incorrectly in the first place.
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Clinical Corner

Clinical Update: Dental Prophylaxis for Infective Endocarditis
Pharmacists should be cognizant of the current guidelines, which may help curtail unnecessary antibiotic use and reduce adverse events and drug resistance.
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Statins for the Treatment of Sepsis
Current research shows a possible benefit of statin therapy and improved outcomes in patients with sepsis, but these data must be better validated through additional clinical trials before this modality can be recommended.
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ScriptPro

It's the Law

Beware of Disability Insurance
As this case demonstrates, it is often difficult to collect long-term benefits, even if you have this coverage through your employer.
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Counseling Pearls

Mitral Valve Prolapse
Most patients with this disease are asymptomatic; however, those with regurgitation may need intervention to prevent or manage complications.
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The New Renin Antagonist: Aliskiren
A look at the first commercially available drug in this class and its place in treating hypertension.
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Tech Talk

Cardinal Health Helps Hospitals Efficiently Order, Store, and Dispense Drugs
Cardinal Health's technologies, services, and expertise enable hospitals to simplify, and thereby improve, their medication management processes.
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US Pharmacist's Platinum Plus MasterCard Credit Card

Educational Spotlight

Advances in the Treatment of Chronic Stable Angina
The ACC/AHA recommended core treatment strategies include beta-blockers, calcium channel blockers, and nitrates, while a recent drug, ranolazine, is FDA-approved as a potential treatment option.
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Evolving Challenges in the Use of Erythropoiesis-Stimulating Agents (ESAs) to Treat Chemotherapy-Induced Anemia
Using clinical knowledge, the pharmacist can monitor dosing and administration of parenteral iron and erythropoietic therapies, monitor for signs and symptoms of adverse drug events, and recommend appropriate interventions to improve patient care.
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Other Featured CEs:

Newswire

U.S. Prescription Drug Use at All-Time High
St. Louis, MO A report by pharmacy benefit manager, Express Scripts, revealed that more U.S. adults are taking prescription drugs than ever before, accounting for $12 billion in additional spending during 2006 alone. The Geographic Variation in Prescription Utilization study uncovered that the number of people with at least one prescription increased from 67% to 74% between 2000 and 2006. This translates to the number of prescriptions per person increasing from 10.8 to 14.3, a 32% increase over the past six years. The study also indicated a correlation between spending for antidiabetic and antihypertensive prescription drugs and rising obesity in the states with the top five obesity rates (West Virginia, Kentucky, Alabama, Mississippi, Louisiana, and Arkansas).

Sea Algae May Be Key to Potent Anticancer Drug
San Diego, CA A team of researchers at the Rebecca and John Moores UCSD Cancer Center at the University of California located here believe they have identified a potent new anticancer drug isolated from a toxic, blue-green algae found in the waters off the coast of Fiji. The somocystinamide A (ScA) compound was found in the cyanobacterium L. majuscula, also known as "mermaid's hair." The researchers found that ScA inhibits neovascularization, the formation of blood vessels that feed tumors, and also has a direct negative impact on tumor cell proliferation. Putting the importance of this discovery into perspective, William Gerwick from the Scripps Institution of Oceanography commented that if a normal-sized swimming pool full of cancer cells were treated with ScA, it would take only 3 mg (about the weight of a grain of rice) to kill all of the cancer cells. According to Dwayne G. Stupack, associate professor of pathology at Moores UCSD Cancer Center, "The compound isn't toxic to the cyanobacteria itself, but activates a 'death pathway,' present in our cells. When the cells of the blood vessels that feed tumors become activated and proliferate, they become especially sensitive to this agent."

Wal-Mart to Open New Prototype In-Store Clinics
Bentonville, AR Wal-Mart plans on opening in-store clinics that will be co-branded with local community hospitals under the banner name, "The Clinic at Wal-Mart." The first stores are scheduled to debut in Atlanta, Little Rock, and Dallas. The retail giant said that it plans on operating 400 such clinics by 2010. It has already signed a letter of intent to work with RediClinic, LLC and local hospital systems to open co-branded, walk-in clinics in 200 Wal-Mart Supercenters. Each clinic will operate seven days a week.

NACDS Debuts Pharmacy Ad Campaign
Bonita Springs, FL A new advertising campaign that stresses the importance of pharmacies to the nation's well being was unveiled at the National Association of Chain Drug Stores' Regional Chain Conference held here. The ads, which feature the tagline "Pharmacies. The Face of Neighborhood Healthcare," highlight the importance of pharmacies and pharmacists, including convenience, accessibility, expertise, prevention of drug interactions, and counseling patients to take their medications as prescribed. The ads are directed toward Capitol Hill, the Executive Branch, the media, and opinion leaders "inside the Beltway" in Washington, DC. They will start appearing next month in local publications, transit settings, and on drive-time radio and online.

Medco Announces National Scholarship Program
Franklin Lakes, NJ Medco Health Solutions will be offering a national scholarship program to identify and support the development of the next generation of pharmacists. According to a company's press release, the program will be conducted through the Medco Labor Coalition, "the nation's only coalition dedicated to providing pharmacy benefits to small and mid-size labor unions." The scholarship is based on a combination of academic achievement, commitment to a career in pharmacy, leadership, and community service. Awardees will be chosen on an annual basis by an independent scholarship service retained by Medco. The application deadline is April 15, 2008. Students can apply online, click here.

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